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title: seqWell Scope
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[![seqWell](https://7918658.fs1.hubspotusercontent-na1.net/hubfs/7918658/logo-seqwell.svg "seqWell")](https://seqwell.com/)

![24-sw-newsletter-seqwell-no-scope](https://7918658.fs1.hubspotusercontent-na1.net/hub/7918658/hubfs/24-sw-newsletter-seqwell-no-scope.png?width=2020&height=474&name=24-sw-newsletter-seqwell-no-scope.png "24-sw-newsletter-seqwell-no-scope")

**October Newsletter**

**In This Issue:**

- All About GUIDE-seq2
- NEW: ExpressPlex™ 2.0 Hidden Savings Infographic
- Recent event: ASHG 2025
- Recent Press Release

**All About GUIDE-seq2**

![All About GUIDE-Seq 2](https://7918658.fs1.hubspotusercontent-na1.net/hub/7918658/hubfs/All%20About%20GUIDE-Seq%202.webp?width=1200&height=590&name=All%20About%20GUIDE-Seq%202.webp "All About GUIDE-Seq 2")

Understanding and minimizing off-target effects is key to advancing gene editing with confidence. In case you missed them, we recently posted two blogs containing insights on [why off-target analysis matters](https://seqwell.com/gaining-confidence-in-gene-editing-off-target-analysis/) and [how to choose the right assay for your gene editing workflows.](https://seqwell.com/guide-to-selecting-right-gene-editing-off-target-assay/)

Don’t miss our third blog in the Gene Editing QC series that highlights GUIDE-seq2 – an approach that takes off-target analysis to the next level. Read the [full blog](https://seqwell.com/bringing-tagmentation-to-guide-seq2/) below to see how GUIDE-seq2 is shaping the future of gene editing analysis.

[Read the full blog](https://seqwell.com/bringing-tagmentation-to-guide-seq2/)

**NEW: ExpressPlex™ 2.0 Hidden Savings Infographic**

[![ExpressPlexTM 2.0 Unseen Savings Infographic](https://7918658.fs1.hubspotusercontent-na1.net/hub/7918658/hubfs/ExpressPlexTM%202.0%20Unseen%20Savings%20Infographic.webp?width=600&height=442&name=ExpressPlexTM%202.0%20Unseen%20Savings%20Infographic.webp "ExpressPlexTM 2.0 Unseen Savings Infographic")](https://seqwell.com/wp-content/uploads/2025/09/ExpressPlex-Hidden-Savings-Clear-Value.pdf)

What if you could save 80% on Library Prep?

The cost of NGS isn’t just about the sequencer or flow cell prices you can see on a purchase order. Generating sequence-ready libraries upstream of sequencing is a key economic driver. Many labs evaluate library prep workflows based only on kit price, but the real cost of library prep includes labor, consumables, and hidden add-ons that don’t show up until you’re knee-deep in the process.

This is where [ExpressPlex™ 2.0](https://seqwell.com/expressplex-2-0-library-prep-kit/) stands apart. Designed to streamline high-throughput DNA library prep from start to finish, it eliminates unnecessary steps, reduces waste, and drastically reduces staff time at the bench compared with alternative library prep methods. For labs watching budgets closely — and for those looking to scale — the return on investment (ROI) is hard to ignore.

Check out our new infographic, which breaks down all the ways you can save by choosing ExpressPlex™ 2.0 for your NGS.

[Download now](https://seqwell.com/wp-content/uploads/2025/09/ExpressPlex-Hidden-Savings-Clear-Value.pdf)

**ASHG 2025**

![25-sw-ashg-social-image-c2-v1a](https://7918658.fs1.hubspotusercontent-na1.net/hub/7918658/hubfs/25-sw-ashg-social-image-c2-v1a.jpg?width=400&height=400&name=25-sw-ashg-social-image-c2-v1a.jpg "25-sw-ashg-social-image-c2-v1a")

![25-sw-ashg-phirx-post-v1a](https://7918658.fs1.hubspotusercontent-na1.net/hub/7918658/hubfs/25-sw-ashg-phirx-post-v1a.webp?width=400&height=400&name=25-sw-ashg-phirx-post-v1a.webp "25-sw-ashg-phirx-post-v1a")

We recently attended ASHG 2025 in Boston, MA where we shared:

- Posters highlighting the latest [MosaiX™](https://seqwell.com/mosaix-library-prep-kit/) High Complexity Library Prep Kit advancements and the [LongPlex™](https://seqwell.com/longplex-multiplexing/) Multiplexing Kit for [PacBio](https://www.pacb.com/) long read sequencing. Check out Posters **4003W** & **4076T.**
- FREE samples of our newly released [PhiRx™](https://seqwell.com/phirx-xleap-sbs-color-balancing/) Indexed Control for improved color balancing of Illumina XLEAP-SBS chemistry.
- **SPECIAL PRICING:** Learn how you can perform high complexity library prep for <$10 per sample using MosaiX™!

Couldn't make it to ASHG? Contact [seqwell](mailto:sales@seqwell.com?subject=Not%20Attending%20ASHG) to discuss how to recieve <$10 per sample pricing.

Want to learn more about MosaiX™ before taking the plunge? We developed a [full product brochure](https://seqwell.com/wp-content/uploads/2025/09/seqWell_MosaiX-Brochure_092025.pdf) to break it down for you!

**Recent Press Release**

[![sw-pacbio](https://7918658.fs1.hubspotusercontent-na1.net/hub/7918658/hubfs/sw-pacbio.png?width=1200&height=673&name=sw-pacbio.png "sw-pacbio")](https://seqwell.com/wp-content/uploads/2024/03/seqWell-LongPlex-Brochure_10_2025.pdf)

**PacBio** is expanding its partnership with seqWell to offer the [LongPlex™ Multiplexing Kit](https://seqwell.com/longplex-multiplexing/) to more labs. Read the full release [here.](https://bit.ly/48Y3z3I) seqWell's highly scalable, cost-effective LongPlex™ kit delivers streamlined tagmentation and multiplexing for low-pass whole genome sequencing, plasmid resequencing, and microbial sequencing.

[View LongPlex™ Product Brochure](https://seqwell.com/wp-content/uploads/2024/03/seqWell-LongPlex-Brochure_10_2025.pdf)

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